CATH Classification

Domain Context

CATH Clusters

Superfamily Ureohydrolase domain
Functional Family Arginase

Enzyme Information

3.5.3.1
Arginase.
based on mapping to UniProt P78540
L-arginine + H(2)O = L-ornithine + urea.
-!- Also hydrolyzes alpha-N-substituted L-arginines and canavanine.

UniProtKB Entries (1)

P78540
ARGI2_HUMAN
Homo sapiens
Arginase-2, mitochondrial

PDB Structure

PDB 1PQ3
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Human Arginase II: Crystal Structure and Physiological Role in Male and Female Sexual Arousal
Cama, E., Colleluori, D.M., Emig, F.A., Shin, H., Kim, S.W., Kim, N.N., Traish, A.M., Ash, D.E., Christianson, D.W.
Biochemistry