CATH Classification

Domain Context

CATH Clusters

Superfamily TolB, C-terminal domain
Functional Family Diisopropyl-fluorophosphatase

Enzyme Information

3.1.8.2
Diisopropyl-fluorophosphatase.
based on mapping to UniProt Q7SIG4
Diisopropyl fluorophosphate + H(2)O = diisopropyl phosphate + fluoride.
-!- Acts on phosphorus anhydride bonds (such as phosphorus-halide and phosphorus-cyanide) in organophosphorus compounds (including nerve gases). -!- Inhibited by chelating agents. -!- Related to EC 3.1.8.1. -!- Formerly EC 3.8.2.1.

UniProtKB Entries (1)

Q7SIG4
DFPA_LOLVU
Loligo vulgaris
Diisopropyl-fluorophosphatase

PDB Structure

PDB 1PJX
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Statistical analysis of crystallographic data obtained from squid ganglion DFPase at 0.85 A resolution.
Koepke, J., Scharff, E.I., Lucke, C., Ruterjans, H., Fritzsch, G.
Acta Crystallogr.,Sect.D