CATH Classification

Domain Context

CATH Clusters

Superfamily CoaB-like
Functional Family Phosphopantothenate--cysteine ligase 2

Enzyme Information

6.3.2.5
Phosphopantothenate--cysteine ligase (CTP).
based on mapping to UniProt Q9HAB8
CTP + (R)-4'-phosphopantothenate + L-cysteine = CMP + diphosphate + N-((R)-4'-phosphopantothenoyl)-L-cysteine.

UniProtKB Entries (1)

Q9HAB8
PPCS_HUMAN
Homo sapiens
Phosphopantothenate--cysteine ligase

PDB Structure

PDB 1P9O
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of human phosphopantothenoylcysteine synthetase at 2.3 A resolution.
Manoj, N., Strauss, E., Begley, T.P., Ealick, S.E.
Structure