CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family S-(hydroxymethyl)glutathione dehydrogenase

Enzyme Information

1.1.1.2
Alcohol dehydrogenase (NADP(+)).
based on mapping to UniProt O57380
An alcohol + NADP(+) = an aldehyde + NADPH.
-!- Some members of this group oxidize only primary alcohols; others act also on secondary alcohols. -!- May be identical with EC 1.1.1.19, EC 1.1.1.33 and EC 1.1.1.55. -!- Re-specific with respect to NADPH.

UniProtKB Entries (1)

O57380
ADH8_PELPE
Pelophylax perezi
NADP-dependent alcohol dehydrogenase

PDB Structure

PDB 1P0F
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the vertebrate NADP(H)-dependent alcohol dehydrogenase (ADH8)
Rosell, A., Valencia, E., Pares, X., Fita, I., Farres, J., Ochoa, W.F.
J.Mol.Biol.