CATH Classification

Domain Context

CATH Clusters

Superfamily Peptidase S8/S53 domain
Functional Family Proteinase K

Enzyme Information

3.4.21.64
Peptidase K.
based on mapping to UniProt P06873
Hydrolysis of keratin, and of other proteins with subtilisin-like specificity. Hydrolyzes peptide amides.
-!- From the mold Tritirachium album Limber. -!- Contains two disulfide bridges and one free Cys near the active site His. -!- Belongs to peptidase family S8. -!- Formerly EC 3.4.4.16 and EC 3.4.21.14.

UniProtKB Entries (1)

P06873
PRTK_PARAQ
Parengyodontium album
Proteinase K

PDB Structure

PDB 1OYO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Regulation of protease activity by melanin: Crystal structure of the complex formed between proteinase K and melanin monomers at 2.0 resolution
Singh, N., Sharma, S., Kumar, S., Raman, G., Singh, T.P.
To be Published