CATH Classification

Domain Context

CATH Clusters

Superfamily Amyloidogenic glycoprotein, copper-binding domain
Functional Family Amyloid beta (A4) protein b

Enzyme Information

UniProtKB Entries (1)

P05067
A4_HUMAN
Homo sapiens
Amyloid-beta precursor protein

PDB Structure

PDB 1OWT
External Links
Method SOLUTION NMR
Organism Pichia
Primary Citation
Structure of the Alzheimer's Disease Amyloid Precursor Protein Copper Binding Domain. A REGULATOR OF NEURONAL COPPER HOMEOSTASIS.
Barnham, K.J., McKinstry, W.J., Multhaup, G., Galatis, D., Morton, C.J., Curtain, C.C., Williamson, N.A., White, A.R., Hinds, M.G., Norton, R.S., Beyreuther, K., Masters, C.L., Parker, M.W., Cappai, R.
J.Biol.Chem.