CATH Classification

Domain Context

CATH Clusters

Superfamily Single helix bin
Functional Family

Enzyme Information

2.7.10.2
Non-specific protein-tyrosine kinase.
based on mapping to UniProt Q05397
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
-!- Unlike EC 2.7.10.1, this protein-tyrosine kinase does not have a transmembrane domain. -!- In the human genome, 32 non-specific protein-tyrosine kinases have been identified and these can be divided into 10 families. -!- Formerly EC 2.7.1.112.

UniProtKB Entries (1)

P49023
PAXI_HUMAN
Homo sapiens
Paxillin

PDB Structure

PDB 1OW7
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Molecular Recognition of Paxillin LD Motifs by the Focal Adhesion Targeting Domain
Hoellerer, M.K., Noble, M.E.M., Labesse, G., Werner, J.M., Arold, S.T.
Structure