1 keywords

CATH Domain 1oshA00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.565 Retinoid X Receptor
Homologous Superfamily 1.10.565.10 Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Bile acid receptor isoform 4

Enzyme Information

UniProtKB Entries (1)

Q96RI1
NR1H4_HUMAN
Homo sapiens
Bile acid receptor

PDB Structure

PDB 1OSH
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR
Downes, M., Verdecia, M.A., Roecker, A.J., Hughes, R., Hogenesch, J.B., Kast-Woelbern, H.R., Bowman, M.E., Ferrer, J.-L., Anisfeld, A.M., Edwards, P.A., Rosenfeld, J.M., Alvarez, J.G., Noel, J.P., Nicolaou, K.C., Evans, R.M.
Mol.Cell