CATH Classification

Domain Context

CATH Clusters

Superfamily 2.80.10.50
Functional Family

Enzyme Information

3.2.2.22
rRNA N-glycosylase.
based on mapping to UniProt P81446
Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
-!- Ricin A-chain and related toxins show this activity. -!- Naked rRNA is attacked more slowly than rRNA in intact ribosomes. -!- Naked rRNA from Escherichia coli is cleaved at a corresponding position.

UniProtKB Entries (1)

P81446
ML1_VISAL
Viscum album
Beta-galactoside-specific lectin 1

PDB Structure

PDB 1ONK
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Mistletoe lectin I from viscum album
Gabdoulkhakov, A.G., Savoshkina, Y., Krauspenhaar, R., Stoeva, S., Konareva, N., Kornilov, V., Kornev, A.N., Voelter, W., Nikonov, S.V., Betzel, C., Mikhailov, A.M.
To be Published