CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.230.10
Functional Family 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Enzyme Information

2.7.1.148
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase.
based on mapping to UniProt Q8FI04
ATP + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = ADP + 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol.
-!- Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis.

UniProtKB Entries (1)

Q8FI04
ISPE_ECOL6
Escherichia coli CFT073
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

PDB Structure

PDB 1OJ4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Biosynthesis of Isoprenoids: Crystal Structure of 4-Diphosphocytidyl-2C-Methyl-D-Erythritol Kinase
Miallau, L., Alphey, M.S., Kemp, L.E., Leonard, G.A., Mcsweeney, S.M., Hecht, S., Bacher, A., Eisenreich, W., Rohdich, F., Hunter, W.N.
Proc.Natl.Acad.Sci.USA