1 keywords

CATH Domain 1oguD01

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.472 Cyclin A; domain 1
Homologous Superfamily 1.10.472.10 Cyclin-like

Domain Context

CATH Clusters

Superfamily Cyclin-like
Functional Family Cyclin-A2

Enzyme Information

UniProtKB Entries (1)

P20248
CCNA2_HUMAN
Homo sapiens
Cyclin-A2

PDB Structure

PDB 1OGU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-Based Design of 2-Arylamino-4-Cyclohexyl Methyl-5-Nitroso-6-Aminopyrimidine Inhibitors of Cyclin-Dependent Kinases 1 and 2
Sayle, K.L., Bentley, J., Boyle, F.T., Calvert, A.H., Cheng, Y., Curtin, N.J., Endicott, J.A., Golding, B.T., Hardcastle, I.R., Jewsbury, P., Mesguiche, V., Newell, D.R., Noble, M.E.M., Parsons, R.J., Pratt, D.J., Wang, L.Z., Griffin, R.J.
Bioorg.Med.Chem.Lett.