CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaredoxin
Functional Family

Enzyme Information

2.5.1.18
Glutathione transferase.
based on mapping to UniProt P30114
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.

UniProtKB Entries (1)

P30114
GST28_SCHHA
Schistosoma haematobium
Glutathione S-transferase class-mu 28 kDa isozyme

PDB Structure

PDB 1OE7
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of the 28 kDa Glutathione S-Transferase from Schistosoma Haematobium
Johnson, K.A., Angelucci, F., Bellelli, A., Herve, M., Fontaine, J., Tsernoglou, D., Capron, A., Trottein, F., Brunori, M.
Biochemistry