CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1350 | Trna Endonuclease; Chain: A, domain 1 |
|
3.40.1350.10 |
Domain Context
CATH Clusters
| Superfamily | 3.40.1350.10 |
| Functional Family |
Enzyme Information
| 3.1.22.4 |
Crossover junction endodeoxyribonuclease.
based on mapping to UniProt Q97YX6
Endonucleolytic cleavage at a junction such as a reciprocal single- stranded crossover between two homologous DNA duplexes (Holliday junction).
-!- The enzyme from Saccharomyces cerevisiae has no endonuclease or exonuclease activity on single-stranded or double-stranded DNA molecules that do not contain Holliday junctions.
|
UniProtKB Entries (1)
| Q97YX6 |
HJE_SACS2
Saccharolobus solfataricus P2
Holliday junction resolvase Hje
|
PDB Structure
| PDB | 1OB8 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Substrate Recognition and Catalysis by the Holliday Junction Resolving Enzyme Hje.
Nucleic Acids Res.
|