CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.2030
Functional Family

Enzyme Information

2.3.1.169
CO-methylating acetyl-CoA synthase.
based on mapping to UniProt P27988
Acetyl-CoA + a [Co(I) corrinoid Fe-S protein] = CO + CoA + a [methyl- Co(III) corrinoid Fe-S protein].
-!- Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO(2) and H(2).

UniProtKB Entries (1)

P27988
DCMA_MOOTH
Moorella thermoacetica
Carbon monoxide dehydrogenase/acetyl-CoA synthase subunit alpha

PDB Structure

PDB 1OAO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Ni-Zn-[Fe4-S4] and Ni-Ni-[Fe4-S4] Clusters in Closed and Open Alpha Subunits of Acetyl-Coa Synthase/Carbon Monoxide Dehydrogenase
Darnault, C., Volbeda, A., Kim, E.J., Legrand, P., Vernede, X., Lindahl, P.A., Fontecilla-Camps, J.C.
Nat.Struct.Biol.