CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.300.10
Functional Family S-adenosylmethionine synthase

Enzyme Information

2.5.1.6
Methionine adenosyltransferase.
based on mapping to UniProt P13444
ATP + L-methionine + H(2)O = phosphate + diphosphate + S-adenosyl-L- methionine.
-!- Formerly EC 2.4.2.13.

UniProtKB Entries (1)

P13444
METK1_RAT
Rattus norvegicus
S-adenosylmethionine synthase isoform type-1

PDB Structure

PDB 1O90
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structures of Methionine Adenosyltransferase Complexed with Substrates and Products Reveal the Methionine-ATP Recognition and Give Insights Into the Catalytic Mechanism
Gonzalez, B., Pajares, M.A., Hermoso, J.A., Guillerm, D., Guillerm, G., Sanz-Aparicio, J.
J.Mol.Biol.