CATH Classification

Domain Context

CATH Clusters

Superfamily Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1
Functional Family Naphthalene 1,2-dioxygenase system, large oxygenase component

Enzyme Information

1.14.12.12
Naphthalene 1,2-dioxygenase.
based on mapping to UniProt P0A110
Naphthalene + NADH + O(2) = (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD(+).
-!- Comprises a multicomponent system, containing a reductase that is an iron-sulfur flavoprotein (FAD; EC 1.18.1.3), an iron-sulfur oxygenase, and ferredoxin.

UniProtKB Entries (1)

P0A112
NDOC_PSEPU
Pseudomonas putida
Naphthalene 1,2-dioxygenase system, small oxygenase component

PDB Structure

PDB 1O7M
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of Naphthalene Dioxygenase: Side-on Binding of Dioxygen to Iron
Karlsson, A., Parales, J.V., Parales, R.E., Gibson, D.T., Eklund, H., Ramaswamy, S.
Science