CATH Classification

Domain Context

CATH Clusters

Superfamily Hypothetical PUA domain-like; domain 1
Functional Family

Enzyme Information

2.1.1.193
16S rRNA (uracil(1498)-N(3))-methyltransferase.
based on mapping to UniProt P44627
S-adenosyl-L-methionine + uracil(1498) in 16S rRNA = S-adenosyl-L- homocysteine + N(3)-methyluracil(1498) in 16S rRNA.
-!- The enzyme specifically methylates uracil(1498) at N(3) in 16S rRNA.

UniProtKB Entries (1)

P44627
RSME_HAEIN
Haemophilus influenzae Rd KW20
Ribosomal RNA small subunit methyltransferase E

PDB Structure

PDB 1NXZ
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Functional assignment based on structural analysis: crystal structure of the yggJ protein (HI0303) of Haemophilus influenzae reveals an RNA methyltransferase with a deep trefoil knot.
Forouhar, F., Shen, J., Xiao, R., Acton, T.B., Montelione, G.T., Tong, L.
Proteins