CATH Classification

Domain Context

CATH Clusters

Superfamily Citrate Synthase, domain 1
Functional Family Citrate synthase

Enzyme Information

2.3.3.16
Citrate synthase (unknown stereospecificity).
based on mapping to UniProt P0ABH7
Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA.
-!- This entry has been included to accommodate those citrate synthases for which the stereospecificity with respect to C(2) of oxaloacetate has not been established (cf. EC 2.3.3.1 and EC 2.3.3.3).

UniProtKB Entries (1)

P0ABH7
CISY_ECOLI
Escherichia coli K-12
Citrate synthase

PDB Structure

PDB 1NXG
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Insights into the evolution of allosteric properties. The NADH binding site of hexameric type II citrate synthases.
Maurus, R., Nguyen, N.T., Stokell, D.J., Ayed, A., Hultin, P.G., Duckworth, H.W., Brayer, G.D.
Biochemistry