CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside diphosphate kinase-like domain
Functional Family Nucleoside diphosphate kinase B

Enzyme Information

2.7.4.6
Nucleoside-diphosphate kinase.
based on mapping to UniProt P22392
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
-!- Many nucleoside diphosphates can act as acceptors. -!- Many ribo- and deoxyribonucleoside triphosphates can act as donors.
2.7.13.3
Histidine kinase.
based on mapping to UniProt P22392
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
-!- This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine). -!- A number of histones can act as acceptor.

UniProtKB Entries (1)

P22392
NDKB_HUMAN
Homo sapiens
Nucleoside diphosphate kinase B

PDB Structure

PDB 1NUE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
X-ray structure of human nucleoside diphosphate kinase B complexed with GDP at 2 A resolution.
Morera, S., Lacombe, M.L., Xu, Y., LeBras, G., Janin, J.
Structure