CATH Classification

Domain Context

CATH Clusters

Superfamily 2.120.10.10
Functional Family

Enzyme Information

3.2.1.18
Exo-alpha-sialidase.
based on mapping to UniProt P27907
Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.
-!- The enzyme does not act on 4-O-acetylated sialic acids. -!- An endo-alpha-sialidase activity is listed as EC 3.2.1.129. -!- See also EC 4.2.2.15.

UniProtKB Entries (1)

P27907
NRAM_INBBE
Influenza B virus (STRAIN B/BEIJING/1/87)
Neuraminidase

PDB Structure

PDB 1NSC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Influenza B virus neuraminidase can synthesize its own inhibitor.
Burmeister, W.P., Henrissat, B., Bosso, C., Cusack, S., Ruigrok, R.W.
Structure