CATH Classification

Domain Context

CATH Clusters

Superfamily Galactose-binding domain-like
Functional Family Rhamnogalacturonate lyase A

Enzyme Information

4.2.2.23
Rhamnogalacturonan endolyase.
based on mapping to UniProt Q00019
Endotype eliminative cleavage of L-alpha-rhamnopyranosyl-(1->4)-alpha-D- galactopyranosyluronic acid bonds of rhamnogalacturonan I domains in ramified hairy regions of pectin leaving L-rhamnopyranose at the reducing end and 4-deoxy-4,5-unsaturated D-galactopyranosyluronic acid at the non- reducing end.
-!- The enzyme is part of the degradation system for rhamnogalacturonan I in Bacillus subtilis strain 168 and Aspergillus aculeatus.

UniProtKB Entries (1)

Q00019
RGLA_ASPAC
Aspergillus aculeatus
Rhamnogalacturonate lyase A

PDB Structure

PDB 1NKG
External Links
Method X-RAY DIFFRACTION
Organism Aspergillus
Primary Citation
Rhamnogalacturonan lyase reveals a unique three-domain modular structure for polysaccharide lyase family 4.
McDonough, M.A., Kadirvelraj, R., Harris, P., Poulsen, J.C., Larsen, S.
Febs Lett.