CATH Classification

Domain Context

CATH Clusters

Superfamily Bira Bifunctional Protein; Domain 2
Functional Family Proline--tRNA ligase

Enzyme Information

6.1.1.15
Proline--tRNA ligase.
based on mapping to UniProt O26708
ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro).

UniProtKB Entries (1)

O26708
SYP_METTH
Methanothermobacter thermautotrophicus str. Delta H
Proline--tRNA ligase

PDB Structure

PDB 1NJ1
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The structural basis of cysteine aminoacylation of tRNAPro by prolyl-tRNA synthetases
Kamtekar, S., Kennedy, W.D., Wang, J., Stathopoulos, C., Soll, D., Steitz, T.A.
Proc.Natl.Acad.Sci.USA