CATH Classification

Domain Context

CATH Clusters

Superfamily PVUII Endonuclease, subunit A
Functional Family

Enzyme Information

3.1.21.4
Type II site-specific deoxyribonuclease.
based on mapping to UniProt P23657
Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.
-!- Large group of enzymes which recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition site. -!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/

UniProtKB Entries (1)

P23657
T2P2_PROHU
Proteus hauseri
Type-2 restriction enzyme PvuII

PDB Structure

PDB 1NI0
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of the Y94F mutant of the restriction endonuclease PvuII
Tucker, P.A., Kokkinidis, M., Nicolaki, S., Kotsifaki, D.
To be Published