CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.465.10
Functional Family Xanthine dehydrogenase, FAD binding subunit

Enzyme Information

1.2.5.3
Aerobic carbon monoxide dehydrogenase.
based on mapping to UniProt P19920
CO + a quinone + H(2)O = CO(2) + a quinol.
-!- This enzyme, found in carboxydotrophic bacteria, catalyzes the oxidation of CO to CO(2) under aerobic conditions. -!- The enzyme belongs to the xanthine oxidoreductase family. -!- The CO(2) that is produced is assimilated by the Calvin-Benson-Basham cycle, while the electrons are transferred to a quinone via the FAD site, and continue through the electron transfer chain to a dioxygen terminal acceptor. -!- Cf. EC 1.2.7.4.

UniProtKB Entries (1)

P19919
DCML_OLICO
Oligotropha carboxidovorans OM5
Carbon monoxide dehydrogenase large chain

PDB Structure

PDB 1N61
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution
Dobbek, H., Gremer, L., Kiefersauer, R., Huber, R., Meyer, O.
Proc.Natl.Acad.Sci.USA