CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Cationic trypsin

Enzyme Information

3.4.21.4
Trypsin.
based on mapping to UniProt P00760
Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.
-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (1)

P00760
TRY1_BOVIN
Bos taurus
Cationic trypsin

PDB Structure

PDB 1MTU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of factor Xa specific inhibitors in complex with trypsin: structural grounds for inhibition of factor Xa and selectivity against thrombin.
Stubbs, M.T., Huber, R., Bode, W.
FEBS Lett.