1 keywords

CATH Domain 1mp5A00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.550 Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Homologous Superfamily 3.90.550.10 Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

Domain Context

CATH Clusters

Superfamily Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Functional Family Glucose-1-phosphate thymidylyltransferase

Enzyme Information

2.7.7.24
Glucose-1-phosphate thymidylyltransferase.
based on mapping to UniProt P26393
dTTP + alpha-D-glucose 1-phosphate = diphosphate + dTDP-alpha-D-glucose.

UniProtKB Entries (1)

P26393
RMLA_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Glucose-1-phosphate thymidylyltransferase

PDB Structure

PDB 1MP5
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering
Barton, W.A., Biggins, J.B., Jiang, J., Thorson, J.S., Nikolov, D.B.
Proc.Natl.Acad.Sci.USA