CATH Classification

Domain Context

CATH Clusters

Superfamily Microbial ribonucleases
Functional Family

Enzyme Information

3.1.27.3
Ribonuclease T(1).
based on mapping to UniProt P30289
Two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in G-P with 2',3'-cyclic phosphate intermediates.
-!- Formerly EC 2.7.7.26 and EC 3.1.4.8.

UniProtKB Entries (1)

P30289
RNS3_KITAU
Kitasatospora aureofaciens
Guanyl-specific ribonuclease Sa3

PDB Structure

PDB 1MGR
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Links X-ray Structure of Two Crystalline Forms of a Streptomycete Ribonuclease with Cytotoxic Activity
Sevcik, J., Urbanikova, L., Leland, P.A., Raines, R.T.
J.Biol.Chem.