CATH Classification

Domain Context

CATH Clusters

Superfamily Doublecortin domain
Functional Family serine/threonine-protein kinase DCLK1 isoform X1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O15075
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

O15075
DCLK1_HUMAN
Homo sapiens
Serine/threonine-protein kinase DCLK1

PDB Structure

PDB 1MG4
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The DCX-domain Tandems of Doublecortin and Doublecortin-like Kinase
Kim, M.H., Cierpickil, T., Derewenda, U., Krowarsch, D., Feng, Y., Devedjiev, Y., Dauter, Z., Walsh, C.A., Otlewski, J., Bushweller, J.H., Derewenda, Z.
Nat.Struct.Biol.