CATH Classification

Domain Context

CATH Clusters

Superfamily Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2
Functional Family

Enzyme Information

1.3.1.98
UDP-N-acetylmuramate dehydrogenase.
based on mapping to UniProt P08373
UDP-N-acetyl-alpha-D-muramate + NADP(+) = UDP-N-acetyl-3- O-(1-carboxyvinyl)-alpha-D-glucosamine + NADPH.
-!- NADH can to a lesser extent replace NADPH. -!- Formerly EC 1.1.1.158.

UniProtKB Entries (1)

P08373
MURB_ECOLI
Escherichia coli K-12
UDP-N-acetylenolpyruvoylglucosamine reductase

PDB Structure

PDB 1MBT
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The structure of the substrate-free form of MurB, an essential enzyme for the synthesis of bacterial cell walls.
Benson, T.E., Walsh, C.T., Hogle, J.M.
Structure