CATH Classification

Domain Context

CATH Clusters

Superfamily SIR2/SIRT2 'Small Domain'
Functional Family

Enzyme Information

3.5.1.-
In linear amides.
based on mapping to UniProt O30124

UniProtKB Entries (2)

P04637
P53_HUMAN
Homo sapiens
Cellular tumor antigen p53
O30124
NPD2_ARCFU
Archaeoglobus fulgidus DSM 4304
NAD-dependent protein deacylase 2

PDB Structure

PDB 1MA3
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of a Sir2 enzyme bound to an acetylated p53 peptide
Avalos, J.L., Celic, I., Muhammad, S., Cosgrove, M.S., Boeke, J.D., Wolberger, C.
Mol.Cell