CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.80 | Trefoil |
|
2.80.10 | Trefoil (Acidic Fibroblast Growth Factor, subunit A) |
|
2.80.10.50 |
Domain Context
CATH Clusters
| Superfamily | 2.80.10.50 |
| Functional Family | Beta-galactoside-specific lectin 1 |
Enzyme Information
| 3.2.2.22 |
rRNA N-glycosylase.
based on mapping to UniProt P81446
Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
-!- Ricin A-chain and related toxins show this activity. -!- Naked rRNA is attacked more slowly than rRNA in intact ribosomes. -!- Naked rRNA from Escherichia coli is cleaved at a corresponding position.
|
UniProtKB Entries (1)
| P81446 |
ML1_VISAL
Viscum album
Beta-galactoside-specific lectin 1
|
PDB Structure
| PDB | 1M2T |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystallisation under microgravity of mistletoe lectin I from Viscum album with adenine monophosphate and the crystal structure at 1.9 A resolution.
Acta Crystallogr.,Sect.D
|