CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.10 | Arc Repressor Mutant, subunit A |
|
1.10.10.490 | Beta-catenin-interacting ICAT |
Domain Context
CATH Clusters
| Superfamily | Beta-catenin-interacting ICAT |
| Functional Family | beta-catenin-interacting protein 1 |
Enzyme Information
UniProtKB Entries (2)
| Q02248 |
CTNB1_MOUSE
Mus musculus
Catenin beta-1
|
| Q9NSA3 |
CNBP1_HUMAN
Homo sapiens
Beta-catenin-interacting protein 1
|
PDB Structure
| PDB | 1M1E |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
ICAT inhibits Beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules.
Mol.Cell
|