CATH Domain 1lrrD00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.1380	Replication modulator SeqA, C-terminal DNA-binding domain
	1.20.1380.10	Replication modulator SeqA, C-terminal DNA-binding domain

Domain Context

CATH Clusters

Superfamily	Replication modulator SeqA, C-terminal DNA-binding domain
Functional Family	Negative modulator of initiation of replication

Enzyme Information

UniProtKB Entries (1)

SEQA_ECOLI

Escherichia coli K-12

Negative modulator of initiation of replication

PDB Structure

PDB	1LRR
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Insights into negative modulation of E. coli replication initiation from the structure of SeqA-hemimethylated DNA complex Guarne, A., Zhao, Q., Guirlando, R., Yang, W. NAT.STRUCT.BIOL.