CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Cationic trypsin

Enzyme Information

3.4.21.4
Trypsin.
based on mapping to UniProt P00760
Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.
-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (1)

P00760
TRY1_BOVIN
Bos taurus
Cationic trypsin

PDB Structure

PDB 1LQE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Design and quantitative structure-activity relationship of 3-amidinobenzyl-1H-indole-2-carboxamides as potent, nonchiral, and selective inhibitors of blood coagulation factor Xa.
Matter, H., Defossa, E., Heinelt, U., Blohm, P.M., Schneider, D., Mueller, A., Herok, S., Schreuder, H.A., Liesum, A., Brachvogel, V., Loenze, P., Walser, A., Al-Obeidi, F., Wildgoose, P.
J.Med.Chem.