CATH Classification

Domain Context

CATH Clusters

Superfamily Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family

Enzyme Information

1.1.1.27
L-lactate dehydrogenase.
based on mapping to UniProt E8ME30
(S)-lactate + NAD(+) = pyruvate + NADH.
-!- Also oxidizes other (S)-2-hydroxymonocarboxylic acids. -!- NADP(+) acts, more slowly, with the animal, but not the bacterial, enzyme.

UniProtKB Entries (1)

E8ME30
LDH2_BIFL2
Bifidobacterium longum subsp. longum JCM 1217
L-lactate dehydrogenase 2

PDB Structure

PDB 1LLD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Molecular basis of allosteric activation of bacterial L-lactate dehydrogenase.
Iwata, S., Ohta, T.
J.Mol.Biol.