CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.530.40
Functional Family

Enzyme Information

3.2.1.17
Lysozyme.
based on mapping to UniProt P00720
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl- D-glucosamine residues in chitodextrins.
-!- Cf. EC 3.2.1.14.

UniProtKB Entries (1)

P00720
ENLYS_BPT4
Escherichia virus T4
Endolysin

PDB Structure

PDB 1L73
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability.
Zhang, X.J., Baase, W.A., Matthews, B.W.
Protein Sci.