CATH Classification

Domain Context

CATH Clusters

Superfamily lambda repressor-like DNA-binding domains
Functional Family HTH-type transcriptional repressor PurR

Enzyme Information

UniProtKB Entries (1)

P03023
LACI_ECOLI
Escherichia coli K-12
Lactose operon repressor

PDB Structure

PDB 1L1M
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Plasticity in protein-DNA recognition: lac repressor interacts with its natural operator 01 through alternative conformations of its DNA-binding domain.
Kalodimos, C.G., Bonvin, A.M., Salinas, R.K., Wechselberger, R., Boelens, R., Kaptein, R.
EMBO J.