CATH Classification

Domain Context

CATH Clusters

Superfamily Phospholipase A2 domain
Functional Family

Enzyme Information

3.1.1.4
Phospholipase A(2).
based on mapping to UniProt P00593
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.

UniProtKB Entries (1)

P00593
PA21B_BOVIN
Bos taurus
Phospholipase A2

PDB Structure

PDB 1KVX
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structures of the catalytic site mutants D99A and H48Q and the calcium-loop mutant D49E of phospholipase A2.
Sekar, K., Biswas, R., Li, Y., Tsai, M., Sundaralingam, M.
Acta Crystallogr.,Sect.D