CATH Classification

Domain Context

CATH Clusters

Superfamily N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
Functional Family 2-dehydropantoate 2-reductase

Enzyme Information

1.1.1.169
2-dehydropantoate 2-reductase.
based on mapping to UniProt P0A9J4
(R)-pantoate + NADP(+) = 2-dehydropantoate + NADPH.

UniProtKB Entries (1)

P0A9J4
PANE_ECOLI
Escherichia coli K-12
2-dehydropantoate 2-reductase

PDB Structure

PDB 1KS9
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of Escherichia coli ketopantoate reductase at 1.7 A resolution and insight into the enzyme mechanism.
Matak-Vinkovic, D., Vinkovic, M., Saldanha, S.A., Ashurst, J.L., von Delft, F., Inoue, T., Miguel, R.N., Smith, A.G., Blundell, T.L., Abell, C.
Biochemistry