CATH Classification

Domain Context

CATH Clusters

Superfamily Dimethylsulfoxide Reductase, domain 2
Functional Family

Enzyme Information

1.17.5.3
Formate dehydrogenase-N.
based on mapping to UniProt P24183
Formate + a quinone = CO(2) + a quinol.
-!- Formate dehydrogenase-N oxidizes formate in the periplasm, transferring electrons via the menaquinone pool in the cytoplasmic membrane to a dissimilatory nitrate reductase (EC 1.7.5.1), which transfers electrons to nitrate in the cytoplasm. -!- The system generates proton motive force under anaerobic conditions. -!- Formerly EC 1.1.5.6.

UniProtKB Entries (1)

P0AAJ3
FDNH_ECOLI
Escherichia coli K-12
Formate dehydrogenase, nitrate-inducible, iron-sulfur subunit

PDB Structure

PDB 1KQF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Molecular basis of proton motive force generation: structure of formate dehydrogenase-N.
Jormakka, M., Tornroth, S., Byrne, B., Iwata, S.
Science