CATH Classification

Domain Context

CATH Clusters

Superfamily Fumarase/aspartase (N-terminal domain)
Functional Family Fumarate hydratase, mitochondrial

Enzyme Information

4.2.1.2
Fumarate hydratase.
based on mapping to UniProt P05042
(S)-malate = fumarate + H(2)O.

UniProtKB Entries (1)

P05042
FUMC_ECOLI
Escherichia coli K-12
Fumarate hydratase class II

PDB Structure

PDB 1KQ7
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
X-ray crystallographic and kinetic correlation of a clinically observed human fumarase mutation.
Estevez, M., Skarda, J., Spencer, J., Banaszak, L., Weaver, T.M.
Protein Sci.