CATH Classification

Domain Context

CATH Clusters

Superfamily Alpha carbonic anhydrase
Functional Family

Enzyme Information

4.2.1.1
Carbonic anhydrase.
based on mapping to UniProt Q50940
H(2)CO(3) = CO(2) + H(2)O.
-!- The enzyme catalyzes the reversible hydration of gaseous CO(2) to carbonic acid, which spontaneously converts to hydrogencarbonate under neutral pH. -!- It is widespread and found in archaea, bacteria, and eukaryotes. -!- Three distinct classes exist, and appear to have evolved independently.

UniProtKB Entries (1)

Q50940
CAH_NEIGO
Neisseria gonorrhoeae
Carbonic anhydrase

PDB Structure

PDB 1KOQ
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of carbonic anhydrase from Neisseria gonorrhoeae and its complex with the inhibitor acetazolamide.
Huang, S., Xue, Y., Sauer-Eriksson, E., Chirica, L., Lindskog, S., Jonsson, B.H.
J.Mol.Biol.