CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Complement factor D

Enzyme Information

3.4.21.39
Chymase.
based on mapping to UniProt P23946
Preferential cleavage: Phe-|-Xaa > Tyr-|-Xaa > Trp-|-Xaa > Leu-|-Xaa.
-!- In mast cell granules. -!- Belongs to peptidase family S1.

UniProtKB Entries (1)

P23946
CMA1_HUMAN
Homo sapiens
Chymase

PDB Structure

PDB 1KLT
External Links
Method X-RAY DIFFRACTION
Organism Bacillus
Primary Citation
Crystal structure of phenylmethanesulfonyl fluoride-treated human chymase at 1.9 A.
McGrath, M.E., Mirzadegan, T., Schmidt, B.F.
Biochemistry