CATH Classification

Domain Context

CATH Clusters

Superfamily Plasminogen Kringle 4
Functional Family Plasminogen

Enzyme Information

3.4.21.7
Plasmin.
based on mapping to UniProt P00747
Preferential cleavage: Lys-|-Xaa > Arg-|-Xaa, higher selectivity than trypsin. Converts fibrin into soluble products.
-!- Formed from plasminogen by proteolysis which results in multiple forms of the active plasmin. -!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.14.

UniProtKB Entries (1)

P00747
PLMN_HUMAN
Homo sapiens
Plasminogen

PDB Structure

PDB 1KI0
External Links
Method X-RAY DIFFRACTION
Organism Pichia
Primary Citation
The X-ray crystallographic structure of the angiogenesis inhibitor angiostatin.
Abad, M.C., Arni, R.K., Grella, D.K., Castellino, F.J., Tulinsky, A., Geiger, J.H.
J.Mol.Biol.