CATH Classification

Domain Context

CATH Clusters

Superfamily 2.60.200.10
Functional Family Mothers against decapentaplegic homolog

Enzyme Information

UniProtKB Entries (1)

Q15796
SMAD2_HUMAN
Homo sapiens
Mothers against decapentaplegic homolog 2

PDB Structure

PDB 1KHX
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-beta signaling.
Wu, J.W., Hu, M., Chai, J., Seoane, J., Huse, M., Li, C., Rigotti, D.J., Kyin, S., Muir, T.W., Fairman, R., Massague, J., Shi, Y.
Mol.Cell