CATH Classification

Domain Context

CATH Clusters

Superfamily DD-peptidase/beta-lactamase superfamily
Functional Family

Enzyme Information

3.5.2.6
Beta-lactamase.
based on mapping to UniProt P00807
A beta-lactam + H(2)O = a substituted beta-amino acid.
-!- Zinc is only requires in class-B enzymes. -!- A group of enzymes of varying specificity hydrolyzing beta-lactams; some act more rapidly on penicillins, some more rapidly on cephalosporins. -!- Formerly EC 3.5.2.8.

UniProtKB Entries (1)

P00807
BLAC_STAAU
Staphylococcus aureus
Beta-lactamase

PDB Structure

PDB 1KGE
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Elimination of the hydrolytic water molecule in a class A beta-lactamase mutant: crystal structure and kinetics.
Zawadzke, L.E., Chen, C.C., Banerjee, S., Li, Z., Wasch, S., Kapadia, G., Moult, J., Herzberg, O.
Biochemistry