CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside diphosphate kinase-like domain
Functional Family Nucleoside diphosphate kinase

Enzyme Information

2.7.4.6
Nucleoside-diphosphate kinase.
based on mapping to UniProt P22887
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
-!- Many nucleoside diphosphates can act as acceptors. -!- Many ribo- and deoxyribonucleoside triphosphates can act as donors.

UniProtKB Entries (1)

P22887
NDKC_DICDI
Dictyostelium discoideum
Nucleoside diphosphate kinase, cytosolic

PDB Structure

PDB 1KDN
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
AlF3 mimics the transition state of protein phosphorylation in the crystal structure of nucleoside diphosphate kinase and MgADP.
Xu, Y.W., Morera, S., Janin, J., Cherfils, J.
Proc.Natl.Acad.Sci.USA