CATH Classification

Domain Context

CATH Clusters

Superfamily DNA polymerase, Y-family, little finger domain
Functional Family

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt P96022
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

P96022
DPO4_SACSO
Saccharolobus solfataricus
DNA polymerase IV

PDB Structure

PDB 1K1Q
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of a DinB family error-prone DNA polymerase from Sulfolobus solfataricus.
Silvian, L.F., Toth, E.A., Pham, P., Goodman, M.F., Ellenberger, T.
Nat.Struct.Biol.