CATH Classification

Domain Context

CATH Clusters

Superfamily 2-enoyl-CoA Hydratase; Chain A, domain 1
Functional Family

Enzyme Information

3.8.1.7
4-chlorobenzoyl-CoA dehalogenase.
based on mapping to UniProt A5JTM5
4-chlorobenzoyl-CoA + H(2)O = 4-hydroxybenzoyl CoA + chloride.
-!- Specific for dehalogenation at the 4-position. -!- Can dehalogenate substrates bearing fluorine, chlorine, bromine and iodine in the 4-position. -!- This enzyme is part of the bacterial 2,4-dichlorobenzoate degradation pathway.

UniProtKB Entries (1)

A5JTM5
CBADH_PSEUC
Pseudomonas sp. CBS3
4-chlorobenzoyl coenzyme A dehalogenase

PDB Structure

PDB 1JXZ
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Histidine 90 Function in 4-chlorobenzoyl-coenzyme A Dehalogenase Catalysis
Zhang, W., Wei, Y., Luo, L., Taylor, K.L., Yang, G., Dunaway-Mariano, D., Benning, M.M., Holden, H.M.
Biochemistry