CATH Classification

Domain Context

CATH Clusters

Superfamily ERV/ALR sulfhydryl oxidase domain
Functional Family Sulfhydryl oxidase

Enzyme Information

1.8.3.2
Thiol oxidase.
based on mapping to UniProt Q12284
2 R'C(R)SH + O(2) = R'C(R)S-S(R)CR' + H(2)O(2).
-!- R may be =S or =O, or a variety of other groups. -!- The enzyme is not specific for R'.

UniProtKB Entries (1)

Q12284
ERV2_YEAST
Saccharomyces cerevisiae S288C
FAD-linked sulfhydryl oxidase ERV2

PDB Structure

PDB 1JR8
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
A new FAD-binding fold and intersubunit disulfide shuttle in the thiol oxidase Erv2p.
Gross, E., Sevier, C.S., Vala, A., Kaiser, C.A., Fass, D.
Nat.Struct.Biol.